SNX: A Potential Drug Target and Biomarker for Various Diseases

Target Name: Sorting nexin

NCBI ID: P48375

Sorting nexin

Other Name(s): SNX | SH3 and PX domain-containing protein | SDP

SNX: A Potential Drug Target and Biomarker for Various Diseases

Sorting Nexin (SNX) is a protein that plays a crucial role in intracellular signaling pathways. It is a subunit of the protein complex known as the Nexin-Cadher complex, which is responsible for regulating cell-cell adhesion. SNX has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

The Nexin-Cadher complex is composed of several proteins that help to regulate the formation and maintenance of tight junctions, which are a type of cell-cell adhesion that is essential for many physiological processes, including cell signaling and tissue structure. The complex includes the cadher protein, which is a transmembrane protein that is involved in cell-cell adhesion, as well as other proteins that help to regulate the activity of the cadher protein.

SNX is a 21-kDa protein that is composed of two distinct subunits, called N-terminal and C-terminal subunits. The N-terminal subunit consists of a unique domain that is involved in the regulation of the activity of the cadher protein. This domain is known as the SNX-domain and is composed of a series of conserved amino acids that are involved in the formation of a protein-protein interaction.

The C-terminal subunit of SNX consists of a shorter protein that is known as the SNX-like domain. This domain is similar to other proteins that are involved in intracellular signaling pathways, including the Src tyrosine kinase, the Fyn protein, and the Src-FAK kinase. The SNX-like domain is involved in the regulation of the activity of the SNX protein and is thought to play a role in the regulation of intracellular signaling pathways.

SNX has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and developmental disorders. For example, studies have shown that SNX is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that targeting SNX may be an effective way to treat these diseases.

In addition to its potential as a drug target, SNX has also been identified as a biomarker for various diseases. For example, studies have shown that SNX is overexpressed in the brains of individuals with Alzheimer's disease, a neurodegenerative disorder. This suggests that targeting SNX may be an effective way to treat this disease.

SNX has also been shown to be involved in the regulation of many intracellular signaling pathways that are important for normal cellular function. For example, studies have shown that SNX is involved in the regulation of the activity of the protein kinase B, which is involved in many cellular signaling pathways. This suggests that targeting SNX may be an effective way to regulate these signaling pathways and treat a wide range of diseases.

In conclusion, SNX is a protein that plays a crucial role in intracellular signaling pathways. It is a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and developmental disorders. Further research is needed to fully understand the role of SNX in these diseases and to develop effective treatments.

Protein Name: Sorting Nexin (nonspecified Subtype)

The "Sorting nexin Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Sorting nexin comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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